MI Paste is a professional tooth remineralizing cream developed by GC America to restore mineral balance in weakened enamel. It contains RECALDENT™ (Casein Phosphopeptide Amorphous Calcium Phosphate or CPP ACP), a milk derived complex that supplies bio available calcium and phosphate ions directly to the tooth surface. Dentists use this advanced topical formula to relieve sensitivity, repair early enamel damage, and protect teeth from acid erosion.
What Is MI Paste?
This water-based dental crème acts as a topical enamel treatment rather than a toothpaste.
Its patented ingredient, CPP ACP, binds strongly to enamel, plaque, and soft tissue, creating a local reservoir of calcium and phosphate.
When applied after brushing, it supports natural enamel remineralization and strengthens tooth surfaces exposed to daily acid attacks.
Key Product Information
| Feature | Details |
|---|---|
| Active Complex | CPP ACP (milk-derived RECALDENT™) |
| Purpose | Sensitivity relief and remineralization |
| Form | Topical dental cream |
| Variants | Original (fluoride free) / Plus (900 ppm fluoride) |
| Manufacturer | GC America Inc. |
How the Formulation Works
The remineralizing process begins when CPP-ACP molecules adhere to enamel and maintain calcium-phosphate ions in a soluble form.
These ions diffuse into microscopic enamel pores caused by acid demineralization, rebuilding the crystalline structure.
In MI Paste Plus, fluoride joins the process to form fluorapatite, which is more resistant to acid attack.
The result is harder enamel, less sensitivity, and improved saliva pH stability.
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Who Benefits from Using MI Paste
Dentists recommend this product for many oral conditions:
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Individuals with sensitive teeth after scaling, polishing, or whitening
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Orthodontic patients prone to white spot lesions near brackets
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People suffering from dry mouth (xerostomia) due to medications or radiotherapy
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Children developing new enamel needing extra protection
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Pregnant women seeking safe, fluoride controlled mineral support
The cream serves as a preventive and therapeutic aid under professional supervision.
Major Benefits
1. Restores Mineral Balance
The CPP ACP complex replenishes calcium and phosphate lost during acid exposure, naturally restoring tooth structure.
2. Reduces Tooth Sensitivity
By sealing exposed dentin tubules, the formula decreases nerve irritation and promotes comfort during eating or brushing.
3. Enhances Whitening Results
Applying the cream after bleaching minimizes post treatment sensitivity and maintains enamel brightness.
4. Stabilizes Oral pH
Its buffering action helps neutralize acids from food and plaque, supporting a healthy oral environment.
5. Non-Invasive and Safe
The product delivers therapeutic effects without drilling or chemical irritation, making it suitable for long-term home care.
How to Use It Properly
Application Steps
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Brush teeth with a fluoride toothpaste.
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Rinse lightly and keep the mouth slightly moist.
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Apply a pea-sized amount of the cream on a clean finger or tray.
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Spread evenly across all tooth surfaces.
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Allow it to remain for at least three minutes without swallowing.
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Avoid food or drink for 30 minutes after application.
Recommended Frequency
| Situation | Frequency | Note |
|---|---|---|
| Post-whitening sensitivity | Once after procedure | Soothes enamel |
| Orthodontic treatment | Nightly | Prevents white spots |
| Dry mouth | Twice daily | Restores minerals |
| Preventive care | Once daily | Maintains enamel strength |
Consistency ensures the best remineralization effect.
Variants Explained
Original Formula
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Fluoride-free, suitable for users who already receive fluoride from other sources.
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Ideal for children or fluoride sensitive individuals.
Plus Formula
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Contains fluoride (900 ppm) for patients at high risk of cavities.
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Promotes fluorapatite formation for stronger enamel defense.
Both versions share identical base chemistry; the difference lies only in fluoride inclusion.
Safety and Precautions
Although clinically safe, users should follow these cautions:
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Avoid use if allergic to milk proteins, since CPP is casein-based.
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Not intended as a toothpaste substitute; use after regular brushing.
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Consult a dentist before introducing it to children under six.
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Store below 25 °C, away from direct heat or sunlight.
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Discontinue if irritation occurs and seek professional advice.
Visible Results and Expected Timeline
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Sensitivity relief: noticeable within three to five applications.
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White-spot improvement: visible after four to six weeks.
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Enamel hardness: measurable increase within one to three months of daily use.
Clinical evidence from university studies confirms that CPP-ACP formulations can reverse early demineralization and enhance fluoride uptake.
Alternative Remineralizing Agents
| Product | Core Ingredient | Mode of Action | Key Difference |
|---|---|---|---|
| MI Paste (Original) | CPP-ACP | Delivers Ca + P ions | No fluoride |
| MI Paste Plus | CPP-ACP + F⁻ | Forms fluorapatite | Added fluoride |
| Nano-Hydroxyapatite Gel | Nano-HA | Fills micro defects | Synthetic base |
| Fluoride Varnish | NaF | Surface coating | Professional only |
Although various products exist, CPP ACP creams remain unique in their bio-availability and enamel adhesion capabilities.
Clinical Research Overview
Research from the University of Melbourne first established the efficacy of CPP-ACP technology.
Peer-reviewed studies in Caries Research and Journal of Dental Research demonstrate that these formulations:
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Increase enamel micro hardness
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Inhibit lesion progression
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Improve fluoride synergy
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Reduce white-spot severity in orthodontic patients
This strong scientific base supports its reputation as a gold-standard remineralization therapy.
Top 5 Professional Reasons to Use It
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Naturally replenishes lost minerals.
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Provides fast and lasting sensitivity relief.
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Enhances the longevity of whitening and bonding.
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Safe for adults, teens, and children under supervision.
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Available with or without fluoride for tailored care.
FAQs:
Q1. Can I use it instead of toothpaste?
No. Brush normally, then apply the cream as a secondary step for mineral delivery.
Q2. Is it suitable for vegans?
No, because its active complex comes from milk casein.
Q3. How long should it stay on teeth?
Leave undisturbed for at least three minutes before spitting out.
Q4. Does it whiten teeth?
Not directly, but by repairing enamel micro-defects, it enhances natural brightness.
Q5. Is it safe during pregnancy?
Yes. The ingredients are non-toxic and suitable under dental supervision.
Q6. Can I use it with aligners or trays?
Yes. Apply a thin layer inside the tray and wear it for several minutes.
See More: Cheapest All on 4: The Definitive Guide to Getting the Best Value
Best Oral Care Routine for Maximum Effect
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Brush twice daily with a fluoride toothpaste.
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Floss to remove plaque between teeth.
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Apply the remineralizing cream nightly before bed.
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Minimize acidic foods and drinks.
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Visit your dentist every six months for professional assessment.
Regular adherence ensures sustained enamel health and long term protection.
Conclusion
The remineralizing cream from GC America remains one of the most effective non-invasive solutions for sensitivity relief and enamel repair. Its CPP ACP technology provides continuous calcium and phosphate release, restoring tooth structure naturally. Whether used alone or alongside fluoride treatments, it offers measurable benefits for patients seeking stronger, smoother, and healthier teeth.
